I run my '87 ETZ 250 on a 30:1 pre-mix ratio with the cheapest mineral 2t motorcycle oil I can find.
Been running for several thousands of miles now, no issue, and no plug fouling. Old articles from the height of the 2t days say 20:1 is the best, end of. But there is ofc a balance is needed and costs decided.
The best way to think about it is: Where does the bike originate, and from what time period, mineral two stroke oil the only thing around in affordable means, and if that was too expensive, they used engine motor oil. And to think, that the quality of the mineral 2t oil now, is far superior then they were ever designed to run on in the first place. The engine itself is also extremely understressed by design for reliability (or possibly, fixibility?
). Fully synth is overkill no doubt, but if it gives you peace of mind that's good.
Regardless though, your decision is all your own, it's a rare bike now, and like has been said probably doesn't cover many miles so what you spend on it in running costs is neither here nor there I gather
Keep that motor running! I love the old ES's!